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Children are less likely to bring Hemophilia

Hemophilia is a genetic disease caused by a deficiency of blood coagulation factors. Hemophilia A occurs when. An anomaly in the gene for the absence of coagulation factor VIII (FVII) Meanwhile hemophilia B caused by a deficiency of coagulation factor IX (FIX). Hemophilia A and B are indistinguishable, since they have similar clinical appearance and a similar pattern of inheritance of genes. The disease is not contagious, but it is difficult to cure or life.

Physical abnormalities depending bleeding will be a bruise on the head or extrinitis. and so often hemartrasi. Of course, there is an area of ​​bruising pain. Rarely gangrene. Bleeding menyebabk muscular interstitial movement can be interrupted and sometimes causes peripheral neuritis.

There are two types of hemophilia:
- Type A, or classic hemophilia, is a deficiency of factor VIII clotting
- Type B is caused by a deficiency of factor IX. These factors are proteins in the blood, which causes problems in the coagulation.

Hemophilia is perhaps the result of a mutation in the gene for factor VIII and IX. And the mutation in the X chromosome

Men marry women with hemophilia health

You think. To the basic principles of heredity Women have a pair of sex chromosomes X and X. While men have one X chromosome and one Y chromosome produced in this view, when he gave the X chromosome, the offspring are girls. When he donated the Y chromosome, joined the young child was.

In other words, every girl a carrier of hemophilia (DRC), the X chromosome inherited from their father, said to be the type of hemophilia. And all the guys will not be affected by hemophilia, because the Y chromosome inherited from his father.

Women married to men with hemophilia health

If you have a child, the child has developed the ability to Hemophilia 50 percent. Receive it depends on the position of the X chromosome in children. When the boy was normal X chromosome inherited from the mother, so he did not. About the characteristics of Hemophilia But if you inherit one X-chromosome carrier of the hemophilia gene from the mother, it brings nature of hemophilia.

When she was a girl, the girl took the type of hemophilia is also 50 percent. Children will be normal if the normal X chromosome inherited from the mother. Instead, he can bring the nature of the X chromosome inherited Hemophilia Hemophilia when Mother Nature.

Although the majority is due to genetic factors, there are cases in which a child with hemophilia and their parents is born healthy families. “It is possible that if there is a mutation in the fetus,” said Chairman of the Indonesian Association of Hemophilia, Professor Djajadiman Billy, SpA (K), in conversation with hemophilia welcome to the world all day on 17 April.

Category: Children, Disease